What is the true cost of a lice infestation? The average amount of time spent battling an infestation on your own is 3-6 months. What about the financial burden? Once you consider money spent on ineffective drugstore treatments, followed by expensive prescription medications, the cost of replacing infested household items, the lost income from missed days of work, and so on, you are looking at over $800 in costs. And there is no guarantee that the infestation will be gone at this point. Not only is battling a lice infestation on your own time-consuming and expensive, but it can also be damaging to your physical and emotional health. Many DIY products contain pesticides and poisonous chemicals that can be harmful to you and your family’s health. Dealing with a lice infestation is also generally emotionally upsetting, causing stress and a loss of sleep.